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Particle Beam Radiation Therapy for
Liver Cancer

Liver Cancer Radiation Therapy Criteria Overview


  • The indication for particle beam radiation therapy is a primary liver cancer (hepatocellular carcinoma) diagnosed pathologically with biopsy or clinically.
  • A clinically diagnosed primary liver cancer must meet all of the following criteria:
    1) Patients of hepatitis C or B
    2) Lectin affinity of AFP isoforms (AFP-L3%) is 15% or higher, or PIVKA-II is 40AU/mL or higher.
    3) Dynamic CT or hepatic artery angiography shows a transient stain in early phase and a low concentration in late phase (60 seconds or later).
  • As a rule, the therapy aims at a solitary liver cancer. However, if multiple satellite lesions exist in subsegments of the liver and if they fall within the same irradiation range, they can be treated. If there is a lesion in the liver that has been treated before, the particle beam must be controlled carefully when radiation therapy starts.

Beam Type No. of Fractions
Proton or carbon-ion 4, 10, 20, or 38

Applicable Stage Histological Type Max. Tumor Diameter Requirements Specific
Ineligibility
Criteria
T1N0M0
T2N0M0
T3N0M0
T4N0M0
Hepatocellular carcinoma 8cm or less Solitary Tumor embolism of the hepatic portal vein. Digestive tract existing within 2cm from the liver cancer. Liver failure (Child-Pugh classification C).
Gastroesophageal varicosity with positive RC signs


Download

You can download the referral forms below. These forms should be submitted at the time of consultation. Left-click on the file link below to download the referral forms. The file will open automatically. To save the file, right-click and select "Save file."

□  Particle Beam Radiation Therapy Referral Fax Form
Small Liver Cancer Check Items/Test Items
[Word Format(46kB)]   [PDF Format(139kB)]

□  Particle Beam Radiation Therapy Referral Fax Form
Locally Developed Liver Cancer Check Items/Test Items
[Word Format(46kB)]   [PDF Format(139kB)]


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