Particle Beam Radiation Therapy for Prostate Cancer / Hyogo Ion Beam Medical Center


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Particle Beam Radiation Therapy for Prostate Cancer

The indication for particle beam radiation therapy is a prostate cancer diagnosed pathologically.
The therapy can be used if there is no lymph node metastasis or no distant metastasis. However, depending on the condition, endocrine therapy may be necessary before particle beam radiation therapy. The length of endocrine therapy varies.
Local-regional prostate cancer, which is a relatively early stage cancer, can be treated by particle beam alone (A).
In some cases, depending on the stage at the time of the diagnosis (before therapy), biopsy result, and the PSA value, it is necessary to perform a 6-month endocrine therapy (hormonal therapy) prior to the particle beam radiation therapy (B, C).
As a general rule, the endocrine therapy will be stopped upon the start of particle beam radiation therapy (A, B).
Some locally advanced prostate cancers (C) require continuation of the endocrine therapy for more than one year after the particle beam radiation therapy.

Prostate Cancer I-II Stage (A) Radiation Therapy Criteria Overview

Beam Type	No. of Fractions
Proton	37

Applicable Stage	Histological Type	Requirements	Specific Ineligibility Criteria
T1N0M0 T2aN0M0 T2bN0M0	Adenocarcinoma	Clinical Stage T1-T2b Systematic biopsy shows the percent for cores positive for adenocarcinoma is 50% or less. PSA value less than 20ng/ml before therapy.	Severe diabetes (HbA1c 8.0% or higher)

Prostate Cancer I-III Stage (B) Radiation Therapy Criteria Overview (Proton Beam)

Beam Type	No. of Fractions
Proton	37
Proton	More than 6 months of endocrine therapy (to be stopped when particle beam radiation therapy starts)

Applicable Stage	Histological Type	Requirement: PSA less than 50ng/ml and none of the following is met.	Specific Ineligibility Criteria
T1N0M0 T2N0M0 T3N0M0	Adenocarcinoma	Clinical stage up to 2b. Systematic biopsy shows the percent for cores positive for adenocarcinoma is 50% or less. PSA value less than 20ng/ml before therapy.	Severe diabetes (HbA1c 8.0% or higher)

Prostate Cancer I-IV Stage (C) Radiation Therapy Criteria Overview (Proton Beam)

Beam Type	No. of Fractions
Proton	39
Proton	More than 6 months of endocrine therapy is performed as pretreatment. After the particle beam radiation therapy, the endocrine therapy is continued for at least one year.

Applicable Stage	Histological Type	Requirements	Specific Ineligibility Criteria
T1N0M0 T2N0M0 T3N0M0 T4N0M0	Adenocarcinoma	PSA maximum 50ng/ml or higher. T4 (invasion to organs other than seminal vesicle).	Lymph node metastasis positive. Distant metastasis positive. Severe diabetes (HbA1c 8.0% or higher)

Download

You can download the referral forms below. These forms should be submitted at the time of consultation.
Left-click on the file link below to download the referral forms. The file will open automatically.
To save the file, right-click and select "Save file."

□	Particle Beam Radiation Therapy Referral Fax Form
	Prostate Cancer Check Items Test Items

[Word Format(48kB)]　　　[PDF Format（135kB）]

1-2-1 Koto, Shingu-cho,
Tatsuno-shi,
Hyogo JAPAN 679-5165
TEL(0791)58-0100（rep.）
FAX(0791)58-2600